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Last updateSun, 04 Feb 2024 4am

Case Study: Improving Biopharmaceutical Process: Level Control of Caustic Soda Solution

A biopharmaceuticals company needed an accurate and repeatable level measurement of caustic soda solution, which was used to control the biopharmaceutical process of continuous fermentation.

The application had been originally equipped with a competitor’s float system, and due to the typical “lift-off” issues that accompany those systems, it only had a measurable level of 5" (13 cm) above the bottom of the storage tank.

Because the storage tank was only 27.5" (70 cm) high, and any leftover solution had to be discarded, it resulted in both wasted process media and loss of yield during fermentation.

The product temperature was about +77° F (+25° C), with a pressure of 18.9 psi (1.3 bar). The container was periodically sterilized at +249.8° F (+ 121° C) for 60 min.

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